Elimination of Schistosoma mansoni Adult Worms by Rhesus Macaques: Basis for a Therapeutic Vaccine?

Among animal models of schistosomiasis, the rhesus macaque is unique in that an infection establishes but egg excretion rapidly diminishes, potentially due to loss of adult worms from the portal system via shunts or death by immune attack.To investigate this, six rhesus macaques were exposed to Schi...

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Bibliographic Details
Main Authors: R Alan Wilson, Jan A M Langermans, Govert J van Dam, Richard A Vervenne, Stephanie L Hall, William C Borges, Gary P Dillon, Alan W Thomas, Patricia S Coulson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2553480?pdf=render