C/EBP homologous protein (CHOP) deficiency aggravates hippocampal cell apoptosis and impairs memory performance.

Neurodegenerative disorders are growing burdens in modern societies because of increased life expectancy. Most neurodegenerative disorders commonly possess a similar neuropathological feature--the accumulation of abnormal protein aggregates or inclusions (misfolded proteins) in the brain. One of the...

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Bibliographic Details
Main Authors: Chang-Mu Chen, Cheng-Tien Wu, Chih-Kang Chiang, Bor-Wu Liao, Shing-Hwa Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3397964?pdf=render