Multi-Modulation of Doxorubicin Resistance in Breast Cancer Cells by Poly(<span style="font-variant: small-caps">l</span>-histidine)-Based Multifunctional Micelles

Even though the reversal of multi-drug resistance (MDR) by numerous nanoparticles has been extensively studied, limited success has been achieved. To overcome this barrier, we report a rationally-designed pH-sensitive micelle, in which doxorubicin (Dox) and resveratrol (Res) were co-loaded. The mice...

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Bibliographic Details
Main Authors: Li Jia, Nan Jia, Yan Gao, Haiyang Hu, Xiuli Zhao, Dawei Chen, Mingxi Qiao
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Pharmaceutics
Subjects:
MDR
Online Access:https://www.mdpi.com/1999-4923/11/8/385