Use of human papillomavirus DNA, E6/E7 mRNA, and p16 immunocytochemistry to detect and predict anal high-grade squamous intraepithelial lesions in HIV-positive and HIV-negative men who have sex with men.

Use of human papillomavirus DNA, E6/E7 mRNA, and p16 immunocytochemistry to detect and predict anal high-grade squamous intraepithelial lesions in HIV-positive and HIV-negative men who have sex with men.

Men who have sex with men (MSM) are at high risk of having anal cancer. Anal high-grade squamous intraepithelial lesion (HSIL) is the precursor of anal cancer. We explored the use of different biomarkers associated with human papillomavirus (HPV) infection and HPV-mediated cell transformation to det...

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Bibliographic Details
Main Authors: Nittaya Phanuphak, Nipat Teeratakulpisarn, Somboon Keelawat, Tippawan Pankam, Jiranuwat Barisri, Surang Triratanachat, Amornrat Deesua, Piyanee Rodbamrung, Jiratchaya Wongsabut, Patou Tantbirojn, Saranya Numto, Preecha Ruangvejvorachai, Praphan Phanuphak, Joel M Palefsky, Jintanat Ananworanich, Stephen J Kerr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827039?pdf=render

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http://europepmc.org/articles/PMC3827039?pdf=render

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