Arterial colony stimulating factor-1 influences atherosclerotic lesions by regulating monocyte migration and apoptosis[S]

Previous studies have shown that colony stimulating factor-1 (CSF-1) deficiency dramatically reduced atherogenesis in mice. In this report we investigate this mechanism and explore a therapeutic avenue based on inhibition of CSF-1 signaling. Lesions from macrophage colony stimulating factor-1 (Csf1)...

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Bibliographic Details
Main Authors: Zory Shaposhnik, Xuping Wang, Aldons J. Lusis
Format: Article
Language:English
Published: Elsevier 2010-07-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520371182