Curcumin Analogues with Aldose Reductase Inhibitory Activity: Synthesis, Biological Evaluation, and Molecular Docking

Curcumin Analogues with Aldose Reductase Inhibitory Activity: Synthesis, Biological Evaluation, and Molecular Docking

Curcumin, a constituent of <i>Curcuma longa</i>, has shown numerous biological and pharmacological activities, including antidiabetic effects. Here, a novel series of curcumin analogues were synthesized and evaluated for in vitro inhibition of aldose reductase (AR), the first and rate-li...

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Bibliographic Details
Main Authors: Dasharath Kondhare, Sushma Deshmukh, Harshad Lade
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Processes
Subjects:
curcumin analogues
aldose reductase inhibitor
antidiabetic
Claisen–Schmidt condensation
molecular docking
Online Access:https://www.mdpi.com/2227-9717/7/7/417

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https://www.mdpi.com/2227-9717/7/7/417

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