Highly Efficient Synthesis of Substituted 3,4-Dihydropyrimidin-2-(1<i>H</i>)-ones (DHPMs) Catalyzed by Hf(OTf)<sub>4</sub>: Mechanistic Insights into Reaction Pathways under Metal Lewis Acid Catalysis and Solvent-Free Conditions
In our studies on the catalytic activity of Group IVB transition metal Lewis acids, Hf(OTf)<sub>4</sub> was identified as a highly potent catalyst for „one-pot, three-component„ Biginelli reaction. More importantly, it was found that solvent-free conditions, in contra...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2019-01-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/24/2/364 |