Serum S100A6 concentration predicts peritoneal tumor burden in mice with epithelial ovarian cancer and is associated with advanced stage in patients.

BACKGROUND:Ovarian cancer is the 5th leading cause of cancer related deaths in women. Five-year survival rates for early stage disease are greater than 94%, however most women are diagnosed in advanced stage with 5 year survival less than 28%. Improved means for early detection and reliable patient...

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Main Authors: Bih-Rong Wei, Shelley B Hoover, Mark M Ross, Weidong Zhou, Francesco Meani, Jennifer B Edwards, Elizabeth I Spehalski, John I Risinger, W Gregory Alvord, Octavio A Quiñones, Claudio Belluco, Luca Martella, Elio Campagnutta, Antonella Ravaggi, Ren-Ming Dai, Paul K Goldsmith, Kevin D Woolard, Sergio Pecorelli, Lance A Liotta, Emanuel F Petricoin, R Mark Simpson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2765613?pdf=render