Controllable Assembly of Hydrophobic Superparamagnetic Iron Oxide Nanoparticle with mPEG-PLA Copolymer and Its Effect on MR Transverse Relaxation Rate

Assembly of individual superparamagnetic iron oxide nanoparticles (SPION) into cluster is an effective way to prepare MRI contrast agent with high relaxivity. In this study, we fabricated SPION clusters with different sizes and configurations by assembly of amphiphilic mPEG-PLA copolymer with hydrop...

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Bibliographic Details
Main Authors: Xuan Xie, Chunfu Zhang
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2011/152524