Probing compression versus stretch activated recruitment of cortical actin and apical junction proteins using mechanical stimulations of suspended doublets

We report an experimental approach to study the mechanosensitivity of cell-cell contact upon mechanical stimulation in suspended cell-doublets. The doublet is placed astride an hourglass aperture, and a hydrodynamic force is selectively exerted on only one of the cells. The geometry of the device co...

Full description

Bibliographic Details
Main Authors: Xumei Gao, Bipul R. Acharya, Wilfried Claude Otto Engl, Richard De Mets, Jean Paul Thiery, Alpha S. Yap, Virgile Viasnoff
Format: Article
Language:English
Published: AIP Publishing LLC 2018-06-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/1.5025216