Evolution of Mutational Landscape and Tumor Immune-Microenvironment in Liver Oligo-Metastatic Colorectal Cancer

Evolution of Mutational Landscape and Tumor Immune-Microenvironment in Liver Oligo-Metastatic Colorectal Cancer

Genetic dynamics underlying cancer progression are largely unknown and several genes involved in highly prevalent illnesses (e.g., hypertension, obesity, and diabetes) strongly concur to cancer phenotype heterogeneity. To study genotype-phenotype relationships contributing to the mutational evolutio...

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Bibliographic Details
Main Authors: Alessandro Ottaiano, Michele Caraglia, Annabella Di Mauro, Gerardo Botti, Angela Lombardi, Jerome Galon, Amalia Luce, Luigi D’Amore, Francesco Perri, Mariachiara Santorsola, Fabienne Hermitte, Giovanni Savarese, Fabiana Tatangelo, Vincenza Granata, Francesco Izzo, Andrea Belli, Stefania Scala, Paolo Delrio, Luisa Circelli, Guglielmo Nasti
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
colorectal cancer
liver metastases
next generation sequencing
<i>KRAS</i>
<i>SMAD4</i>
Online Access:https://www.mdpi.com/2072-6694/12/10/3073

Internet

https://www.mdpi.com/2072-6694/12/10/3073

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