MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria

MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria

Fas apoptotic signaling regulates diverse physiological processes. Acute activation of Fas signaling triggers massive apoptosis in liver. Upon Fas receptor stimulation, the BH3-only protein Bid is cleaved into the active form, tBid. Subsequent tBid recruitment to mitochondria, which is facilitated b...

Full description

Bibliographic Details
Main Authors: Chong Teik Tan, Qi-Ling Zhou, Yu-Chin Su, Nai Yang Fu, Hao-Chun Chang, Ran N. Tao, Sunil K. Sukumaran, Shairaz Baksh, Yee-Joo Tan, Kanaga Sabapathy, Chun-Dong Yu, Victor C. Yu
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716306817

Internet

http://www.sciencedirect.com/science/article/pii/S2211124716306817

Similar Items