Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

Programmed cell death plays crucial roles in organismal development and host defense. Recent studies have highlighted mechanistic overlaps and extensive, multifaceted crosstalk between pyroptosis, apoptosis, and necroptosis, three programmed cell death pathways traditionally considered autonomous. T...

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Bibliographic Details
Main Authors: Shelbi Christgen, Min Zheng, Sannula Kesavardhana, Rajendra Karki, R. K. Subbarao Malireddi, Balaji Banoth, David E. Place, Benoit Briard, Bhesh Raj Sharma, Shraddha Tuladhar, Parimal Samir, Amanda Burton, Thirumala-Devi Kanneganti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
PANoptosis
PANoptosome
NLRP3
ASC
RIPK1
RIPK3
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00237/full

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