Advances in Understanding Activation and Function of the NLRC4 Inflammasome

by Balamurugan Sundaram, Thirumala-Devi Kanneganti
Published 2021-01-01

From pyroptosis, apoptosis and necroptosis to PANoptosis: A mechanistic compendium of programmed cell death pathways

by Yaqiu Wang, Thirumala-Devi Kanneganti
Published 2021-01-01

Metabolic regulation of pyroptotic cell death expands the therapeutic landscape for treating inflammatory disease

by David E. Place, Thirumala-Devi Kanneganti
Published 2021-01-01

The NLRC4 inflammasome requires IRF8-dependent production of NAIPs

by Ein Lee, Rajendra Karki, Thirumala-Devi Kanneganti
Published 2018-05-01

Innate Immune Pathways in Host Defense

by Thirumala-Devi Kanneganti, Mohamed Lamkanfi, Amal O. Amer
Published 2012-01-01

Role of inflammasomes/pyroptosis and PANoptosis during fungal infection.

by Benoit Briard, R K Subbarao Malireddi, Thirumala-Devi Kanneganti
Published 2021-03-01

The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

by Parimal Samir, R. K. Subbarao Malireddi, Thirumala-Devi Kanneganti
Published 2020-06-01

ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis)

by R. K. Subbarao Malireddi, Sannula Kesavardhana, Thirumala-Devi Kanneganti
Published 2019-11-01

Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection

by Qifan Zhu, Si Ming Man, Rajendra Karki, R.K. Subbarao Malireddi, Thirumala-Devi Kanneganti
Published 2018-03-01

Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins

by David E. Place, R. K. Subbarao Malireddi, Jieun Kim, Peter Vogel, Masahiro Yamamoto, Thirumala-Devi Kanneganti
Published 2021-01-01

The malarial host-targeting signal is conserved in the Irish potato famine pathogen.

by Souvik Bhattacharjee, N Luisa Hiller, Konstantinos Liolios, Joe Win, Thirumala-Devi Kanneganti, Carolyn Young, Sophien Kamoun, Kasturi Haldar
Published 2006-05-01

Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection.

by Christopher R Lupfer, Paras K Anand, Zhiping Liu, Kate L Stokes, Peter Vogel, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Published 2014-09-01

Membrane damage during Listeria monocytogenes infection triggers a caspase-7 dependent cytoprotective response.

by Sara K B Cassidy, Jon A Hagar, Thirumala Devi Kanneganti, Luigi Franchi, Gabriel Nuñez, Mary X D O'Riordan
Published 2012-01-01

Enhanced IL-1β production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae.

by Angeline E Rodriguez, Christopher Bogart, Christopher M Gilbert, Jonathan A McCullers, Amber M Smith, Thirumala-Devi Kanneganti, Christopher R Lupfer
Published 2019-01-01

Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice.

by Jianqiu Xiao, Chun Wang, Juo-Chin Yao, Yael Alippe, Canxin Xu, Dustin Kress, Roberto Civitelli, Yousef Abu-Amer, Thirumala-Devi Kanneganti, Daniel C Link, Gabriel Mbalaviele
Published 2018-11-01

The NLRP3 Inflammasome Promotes Age-Related Thymic Demise and Immunosenescence

by Yun-Hee Youm, Thirumala-Devi Kanneganti, Bolormaa Vandanmagsar, Xuewei Zhu, Anthony Ravussin, Ayinuer Adijiang, John S. Owen, Michael J. Thomas, Joseph Francis, John S. Parks, Vishwa Deep Dixit
Published 2012-01-01

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.

by David E Place, Benoit Briard, Parimal Samir, Rajendra Karki, Anannya Bhattacharya, Clifford S Guy, Jennifer L Peters, Sharon Frase, Peter Vogel, Geoffrey Neale, Masahiro Yamamoto, Thirumala-Devi Kanneganti
Published 2020-03-01

Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins

by Ryan Finethy, Sarah Luoma, Nichole Orench-Rivera, Eric M. Feeley, Arun K. Haldar, Masahiro Yamamoto, Thirumala-Devi Kanneganti, Meta J. Kuehn, Jorn Coers, David S. Weiss, Eric J. Rubin
Published 2017-10-01

Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)

by Shelbi Christgen, Min Zheng, Sannula Kesavardhana, Rajendra Karki, R. K. Subbarao Malireddi, Balaji Banoth, David E. Place, Benoit Briard, Bhesh Raj Sharma, Shraddha Tuladhar, Parimal Samir, Amanda Burton, Thirumala-Devi Kanneganti
Published 2020-05-01

MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response.

by Thomas J Cremer, David H Ravneberg, Corey D Clay, Melissa G Piper-Hunter, Clay B Marsh, Terry S Elton, John S Gunn, Amal Amer, Thirumala-Devi Kanneganti, Larry S Schlesinger, Jonathan P Butchar, Susheela Tridandapani
Published 2009-12-01