Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions.

by Joseph Ryan Krambs, Grazia Abou Ezzi, Juo-Chin Yao, Daniel C Link
Published 2020-01-01

Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice.

by Jianqiu Xiao, Chun Wang, Juo-Chin Yao, Yael Alippe, Canxin Xu, Dustin Kress, Roberto Civitelli, Yousef Abu-Amer, Thirumala-Devi Kanneganti, Daniel C Link, Gabriel Mbalaviele
Published 2018-11-01

Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.

by Jianqiu Xiao, Chun Wang, Juo-Chin Yao, Yael Alippe, Tong Yang, Dustin Kress, Kai Sun, Kourtney L Kostecki, Joseph B Monahan, Deborah J Veis, Yousef Abu-Amer, Daniel C Link, Gabriel Mbalaviele
Published 2020-08-01

TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment

by Bac Viet Le, Paulina Podszywalow-Bartnicka, Silvia Maifrede, Katherine Sullivan-Reed, Margaret Nieborowska-Skorska, Konstantin Golovine, Juo-Chin Yao, Reza Nejati, Kathy Q. Cai, Lisa Beatrice Caruso, Julian Swatler, Michal Dabrowski, Zhaorui Lian, Peter Valent, Elisabeth M. Paietta, Ross L. Levine, Hugo F. Fernandez, Martin S. Tallman, Mark R. Litzow, Jian Huang, Grant A. Challen, Daniel Link, Italo Tempera, Mariusz A. Wasik, Katarzyna Piwocka, Tomasz Skorski
Published 2020-10-01