High-throughput detection of induced mutations and natural variation using KeyPoint technology.

High-throughput detection of induced mutations and natural variation using KeyPoint technology.

Reverse genetics approaches rely on the detection of sequence alterations in target genes to identify allelic variants among mutant or natural populations. Current (pre-) screening methods such as TILLING and EcoTILLING are based on the detection of single base mismatches in heteroduplexes using end...

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Bibliographic Details
Main Authors: Diana Rigola, Jan van Oeveren, Antoine Janssen, Anita Bonné, Harrie Schneiders, Hein J A van der Poel, Nathalie J van Orsouw, René C J Hogers, Michiel T J de Both, Michiel J T van Eijk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2654077?pdf=render

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http://europepmc.org/articles/PMC2654077?pdf=render

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