Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells

The adenomatous polyposis coli (APC) tumour suppressor gene is mutated in about 80% of colorectal cancers (CRC) Brannon et al. (2014) [1]. APC is a large multifunctional protein that regulates many biological functions including Wnt signalling (through the regulation of beta-catenin stability) Reya...

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Bibliographic Details
Main Authors: Lauren E. King, Christopher G. Love, Oliver M. Sieber, Maree C. Faux, Antony W. Burgess
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Genomics Data
Online Access:http://www.sciencedirect.com/science/article/pii/S221359601630023X