Copy number variation profiling in pharmacogenetics CYP-450 and GST genes in Colombian population

Copy number variation profiling in pharmacogenetics CYP-450 and GST genes in Colombian population

Abstract Background Copy Number variation (CNVs) in genes related to drug absorption, distribution, metabolism and excretion (ADME) are relevant in the interindividual variability of drug response. Studies of the CNVs in ADME genes in Latin America population are lacking. The objective of the study...

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Bibliographic Details
Main Authors: Brian Ramírez, María José Niño-Orrego, Daniel Cárdenas, Kevin Enrique Ariza, Karol Quintero, Nora Constanza Contreras Bravo, Caroll Tamayo-Agudelo, María Alejandra González, Paul Laissue, Dora Janeth Fonseca Mendoza
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Medical Genomics
Subjects:
DNA copy number variation
Allele frequency
Personalized medicine
Pharmacogenomics,DNA
Online Access:http://link.springer.com/article/10.1186/s12920-019-0556-x

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http://link.springer.com/article/10.1186/s12920-019-0556-x

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