A novel tetracycline-responsive transgenic mouse strain for skeletal muscle-specific gene expression

A novel tetracycline-responsive transgenic mouse strain for skeletal muscle-specific gene expression

Abstract Background The tetracycline-responsive system (Tet-ON/OFF) has proven to be a valuable tool for manipulating gene expression in an inducible, temporal, and tissue-specific manner. The purpose of this study was to create and characterize a new transgenic mouse strain utilizing the human skel...

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Bibliographic Details
Main Authors: Masahiro Iwata, Davis A. Englund, Yuan Wen, Cory M. Dungan, Kevin A. Murach, Ivan J. Vechetti, Christopher B. Mobley, Charlotte A. Peterson, John J. McCarthy
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Skeletal Muscle
Subjects:
Skeletal muscle-specific
Tetracycline-responsive
Online Access:http://link.springer.com/article/10.1186/s13395-018-0181-y

Internet

http://link.springer.com/article/10.1186/s13395-018-0181-y

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