Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation
<p>Abstract</p> <p>Background</p> <p>In sickle cell disease (SCD), the mitogen-activated protein kinase (MAPK) ERK1/2 is constitutively active and can be inducible by agonist-stimulation only in sickle but not in normal human red blood cells (RBCs). ERK1/2 is involved i...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2013-01-01
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Series: | Clinical Proteomics |
Subjects: | |
Online Access: | http://www.clinicalproteomicsjournal.com/content/10/1/1 |