Systemically delivered antibody-labeled magnetic iron oxide nanoparticles are less toxic than plain nanoparticles when activated by alternating magnetic fields

Systemically delivered antibody-labeled magnetic iron oxide nanoparticles are less toxic than plain nanoparticles when activated by alternating magnetic fields

Objective Toxicity from off-target heating with magnetic hyperthermia (MHT) is generally assumed to be understood. MHT research focuses on development of more potent heating magnetic iron oxide nanoparticles (MIONs), yet our understanding of factors that define biodistribution following systemic del...

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Bibliographic Details
Main Authors: Chun-Ting Yang, Preethi Korangath, Jackie Stewart, Chen Hu, Wei Fu, Cordula Grüttner, Sarah E. Beck, Feng-Huei Lin, Robert Ivkov
Format: Article
Language:English
Published: Taylor & Francis Group 2020-12-01
Series:International Journal of Hyperthermia
Subjects:
iron oxide nanoparticles
magnetic nanoparticles
monoclonal antibody
alternating magnetic fields
hyperthermia
Online Access:http://dx.doi.org/10.1080/02656736.2020.1776901

Internet

http://dx.doi.org/10.1080/02656736.2020.1776901

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