Effect of COX-2 inhibition on tendon-to-bone healing and PGE2 concentration after anterior cruciate ligament reconstruction

Effect of COX-2 inhibition on tendon-to-bone healing and PGE2 concentration after anterior cruciate ligament reconstruction

Abstract Background Non-steroidal anti-inflammatory drugs are commonly used to reduce pain and inflammation in orthopaedic patients. Selective cyclooxygenase-2 (COX-2) inhibitors have been developed to minimize drug-specific side effects. However, they are suspected to impair both bone and tendon he...

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Bibliographic Details
Main Authors: Martin Sauerschnig, Josef Stolberg-Stolberg, Carmen Schmidt, Valerie Wienerroither, Michael Plecko, Karin Schlichting, Carsten Perka, Christian Dynybil
Format: Article
Language:English
Published: BMC 2018-01-01
Series:European Journal of Medical Research
Subjects:
Anterior cruciate ligament
Tendon-to-bone healing
Prostaglandin E2
Cyclooxygenase-2 inhibitor
Online Access:http://link.springer.com/article/10.1186/s40001-017-0297-2

Internet

http://link.springer.com/article/10.1186/s40001-017-0297-2

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