Anti-oncogenic and pro-differentiation effects of clorgyline, a monoamine oxidase A inhibitor, on high grade prostate cancer cells

<p>Abstract</p> <p>Background</p> <p>Monoamine oxidase A (MAO-A), a mitochondrial enzyme that degrades monoamines including neurotransmitters, is highly expressed in basal cells of the normal human prostatic epithelium and in poorly differentiated (Gleason grades 4 and...

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Bibliographic Details
Main Authors: Flamand Vincent, Zhao Hongjuan, Peehl Donna M
Format: Article
Language:English
Published: BMC 2009-08-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/2/55