Ratio of intratumoral macrophage phenotypes is a prognostic factor in epithelioid malignant pleural mesothelioma.

Ratio of intratumoral macrophage phenotypes is a prognostic factor in epithelioid malignant pleural mesothelioma.

HYPOTHESIS:The tumor micro-environment and especially the different macrophage phenotypes appear to be of great influence on the behavior of multiple tumor types. M1 skewed macrophages possess anti-tumoral capacities, while the M2 polarized macrophages have pro-tumoral capacities. We analyzed if the...

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Bibliographic Details
Main Authors: Robin Cornelissen, Lysanne A Lievense, Alexander P Maat, Rudi W Hendriks, Henk C Hoogsteden, Ad J Bogers, Joost P Hegmans, Joachim G Aerts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4156398?pdf=render

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http://europepmc.org/articles/PMC4156398?pdf=render

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