A postsynthetically 2’-“clickable” uridine with arabino configuration and its application for fluorescent labeling and imaging of DNA

The arabino-configured analog of uridine with a propargyl group at the 2’-position was synthesized and incorporated into DNA by solid-phase chemistry. The fluorescence quantum yields of DNA strands that were postsynthetically modified by blue and green emitting cyanine-styryl dyes were improved due...

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Bibliographic Details
Main Authors: Heidi-Kristin Walter, Bettina Olshausen, Ute Schepers, Hans-Achim Wagenknecht
Format: Article
Language:English
Published: Beilstein-Institut 2017-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.13.16