ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion

ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion

Abstract Background To examine the expression of ADAM-17 in rheumatoid arthritis (RA) biological fluids and the role it plays in monocyte adhesion to RA fibroblast-like synoviocytes (FLSs). Methods ADAM-17 expression was measured by enzyme-linked immunosorbent assays (ELISAs) in serum from normal (N...

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Bibliographic Details
Main Authors: Sho Ishii, Takeo Isozaki, Hidekazu Furuya, Hiroko Takeuchi, Yumi Tsubokura, Katsunori Inagaki, Tsuyoshi Kasama
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Arthritis Research & Therapy
Subjects:
ADAM-17
Rheumatoid arthritis
Cell adhesion
Cytokines
Online Access:http://link.springer.com/article/10.1186/s13075-018-1657-1

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http://link.springer.com/article/10.1186/s13075-018-1657-1

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