DNA-binding proteins essential for protein-primed bacteriophage ø29 DNA replication

Bacillus subtilis phage Φ29 has a linear, double-stranded DNA 19 kb long with an inverted terminal repeat of 6 nucleotides and a protein covalently linked to the 5’ ends of the DNA. This protein, called terminal protein (TP), is the primer for the initiation of replication, a reaction catalyzed by t...

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Bibliographic Details
Main Authors: Margarita Salas, Isabel Holguera, Modesto Redrejo-Rodriguez, Miguel De Vega
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2016.00037/full