Myofibroblast modulation of cardiac myocyte structure and function

Abstract After myocardial infarction, resident fibroblasts (Fb) differentiate towards myofibroblasts (MyoFb), generating the scar tissue and the interstitial fibrosis seen in the adjacent myocardium. Fb and MyoFb have the potential to interact with cardiac myocytes (CMs) but insight into the phenoty...

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Bibliographic Details
Main Authors: Chandan K. Nagaraju, Eef Dries, Guillaume Gilbert, Mouna Abdesselem, Nan Wang, Matthew Amoni, Ronald B. Driesen, Karin R. Sipido
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-45078-2