Fluorescent analogues of BeKm-1 with high and specific activity against the hERG channel

Peptidic toxins that target specifically mammalian channels and receptors can be found in the venom of animals. These toxins are rarely used directly as tools for biochemical experiments, and need to be modified via the attachment of chemical groups (e.g., radioactive or fluorescent moieties). Ideal...

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Bibliographic Details
Main Authors: Lucie Vasseur, Alain Chavanieu, Stéphanie Combemale, Cécile Caumes, Rémy Béroud, Michel De Waard, Pierre Ducrot, Jean A. Boutin, Gilles Ferry, Thierry Cens
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Toxicon: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590171019300074