Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability.

Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability.

Genomic imprinting is important for normal brain development and aberrant imprinting has been associated with impaired cognition. We studied the imprinting status in selected imprints (H19, IGF2, SNRPN, PEG3, MEST1, NESPAS, KvDMR, IG-DMR and ZAC1) by pyrosequencing in blood samples from longitudinal...

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Main Authors: Marlene Lorgen-Ritchie, Alison D Murray, Anne C Ferguson-Smith, Marcus Richards, Graham W Horgan, Louise H Phillips, Gwen Hoad, Ishbel Gall, Kristina Harrison, Geraldine McNeill, Mitsuteru Ito, Paul Haggarty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211799

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https://doi.org/10.1371/journal.pone.0211799

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