Dynamical Boolean Modeling of Immunogenic Cell Death

Dynamical Boolean Modeling of Immunogenic Cell Death

As opposed to the standard tolerogenic apoptosis, immunogenic cell death (ICD) constitutes a type of cellular demise that elicits an adaptive immune response. ICD has been characterized in malignant cells following cytotoxic interventions, such as chemotherapy or radiotherapy. Briefly, ICD of cancer...

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Bibliographic Details
Main Authors: Andrea Checcoli, Jonathan G. Pol, Aurelien Naldi, Vincent Noel, Emmanuel Barillot, Guido Kroemer, Denis Thieffry, Laurence Calzone, Gautier Stoll
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physiology
Subjects:
logical modeling
immunogenic cell death
antitumor immune response
dendritic cells
cytotoxic CD8+ T lymphocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.590479/full

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https://www.frontiersin.org/articles/10.3389/fphys.2020.590479/full

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