The Substrates of Nonsense-Mediated mRNA Decay in Caenorhabditis elegans

The Substrates of Nonsense-Mediated mRNA Decay in Caenorhabditis elegans

Nonsense-mediated mRNA decay (NMD) is a conserved pathway that strongly influences eukaryotic gene expression. Inactivating or inhibiting NMD affects the abundance of a substantial fraction of the transcriptome in numerous species. Transcripts whose abundance is altered in NMD-deficient cells may re...

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Bibliographic Details
Main Authors: Virginia S. Muir, Audrey P. Gasch, Philip Anderson
Format: Article
Language:English
Published: Oxford University Press 2018-01-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Nonsense-mediated mRNA decay (NMD)
UPF1/SMG-2
RNA-Seq
C. elegans
post-transcriptional gene regulation
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300254

Internet

http://g3journal.org/lookup/doi/10.1534/g3.117.300254

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