Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis

Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) can enter the body through multiple routes, including via specialized transcytotic cells called microfold cells (M cell). However, the mechanistic basis for M cell entry remains undefined. Here, we show that M cell transcytosis depends on the Mtb Type VII secretion m...

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Bibliographic Details
Main Authors: Haaris S Khan, Vidhya R Nair, Cody R Ruhl, Samuel Alvarez-Arguedas, Jorge L Galvan Rendiz, Luis H Franco, Linzhang Huang, Philip W Shaul, Jiwoong Kim, Yang Xie, Ron B Mitchell, Michael U Shiloh
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
microfold cell
mucosal immunology
Mycobacterium tuberculosis
scavenger receptor
Type VII secretion system
EsxA
Online Access:https://elifesciences.org/articles/52551

Internet

https://elifesciences.org/articles/52551

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