Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) can enter the body through multiple routes, including via specialized transcytotic cells called microfold cells (M cell). However, the mechanistic basis for M cell entry remains undefined. Here, we show that M cell transcytosis depends on the Mtb Type VII secretion m...
Main Authors: | Haaris S Khan, Vidhya R Nair, Cody R Ruhl, Samuel Alvarez-Arguedas, Jorge L Galvan Rendiz, Luis H Franco, Linzhang Huang, Philip W Shaul, Jiwoong Kim, Yang Xie, Ron B Mitchell, Michael U Shiloh |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-03-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/52551 |
Similar Items
-
EsxA might as a virulence factor induce antibodies in patients with Staphylococcus aureus infection
by: Huiqin Zhou, et al.
Published: (2013-01-01) -
Phthiocerol Dimycocerosates From Mycobacterium tuberculosis Increase the Membrane Activity of Bacterial Effectors and Host Receptors
by: Jacques Augenstreich, et al.
Published: (2020-08-01) -
EsxA mainly contributes to the miR-155 overexpression in human monocyte-derived macrophages and potentially affect the immune mechanism of macrophages through miRNA dysregulation
by: Myrna Guadalupe Bonilla-Muro, et al.
Published: (2021-04-01) -
Cloning and expression of the EsxA gene and the growth-promoting effects of the encoded protein on rice seedlings
by: Wen-qing Yu, et al.
Published: (2021-05-01) -
Development of an In Vitro Membrane Model to Study the Function of EsxAB Heterodimer and Establish the Role of EsxB in Membrane Permeabilizing Activity of <i>Mycobacterium tuberculosis</i>
by: Salvador Vazquez Reyes, et al.
Published: (2020-12-01)