Germline EMSY sequence alterations in hereditary breast cancer and ovarian cancer families

Germline EMSY sequence alterations in hereditary breast cancer and ovarian cancer families

Abstract Background BRCA1 and BRCA2 mutations explain approximately one-fifth of the inherited susceptibility in high-risk Finnish hereditary breast and ovarian cancer (HBOC) families. EMSY is located in the breast cancer-associated chromosomal region 11q13. The EMSY gene encodes a BRCA2-interacting...

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Bibliographic Details
Main Authors: Kirsi M. Määttä, Riikka Nurminen, Minna Kankuri-Tammilehto, Anne Kallioniemi, Satu-Leena Laasanen, Johanna Schleutker
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Cancer
Subjects:
Breast cancer
Ovarian cancer
Germline
EMSY
Online Access:http://link.springer.com/article/10.1186/s12885-017-3488-x

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http://link.springer.com/article/10.1186/s12885-017-3488-x

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