Investigation of purification process stresses on erythropoietin peptide mapping profile

Background: Full compliance of recombinant protein peptide mapping chromatogram with the standard reference material, is one of the most basic quality control tests of biopharmaceuticals. Changing a single amino acid substitution or side chain diversity for a given peptide changes protein hydrophobi...

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Bibliographic Details
Main Authors: Mina Sepahi, Hooman Kaghazian, Shahin Hadadian, Dariush Norouzian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Advanced Biomedical Research
Subjects:
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2015;volume=4;issue=1;spage=114;epage=114;aulast=Sepahi