Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques.

Activation of the transcription factor NF-κB appears to be involved in different stages of atherogenesis. In this paper we investigate the role of NF-κB inhibitor IκBα in atherosclerosis. Myeloid-specific deletion of IκBα results in larger and more advanced lesions in LDL-R-deficient mice without af...

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Bibliographic Details
Main Authors:	Pieter Goossens, Monique N Vergouwe, Marion J J Gijbels, Danielle M J Curfs, Johannes H G van Woezik, Marten A Hoeksema, Sofia Xanthoulea, Pieter J M Leenen, Rudolf A Rupec, Marten H Hofker, Menno P J de Winther
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3141029?pdf=render

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http://europepmc.org/articles/PMC3141029?pdf=render

Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques.

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