Quorum Sensing Extracellular Death Peptides Enhance the Endoribonucleolytic Activities of Mycobacterium tuberculosis MazF Toxins

Quorum Sensing Extracellular Death Peptides Enhance the Endoribonucleolytic Activities of Mycobacterium tuberculosis MazF Toxins

mazEF is a toxin-antitoxin module located on chromosomes of most bacteria. MazF toxins are endoribonucleases antagonized by MazE antitoxins. Previously, we characterized several quorum sensing peptides called "extracellular death factors" (EDFs). When secreted from bacterial cultures, EDFs...

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Bibliographic Details
Main Authors: Akanksha Nigam, Sathish Kumar, Hanna Engelberg-Kulka
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
extracellular death peptides
Mycobacterium tuberculosis
quorum sensing
Online Access:https://doi.org/10.1128/mBio.00685-18

Internet

https://doi.org/10.1128/mBio.00685-18

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