Biological Evaluation of Oxindole Derivative as a Novel Anticancer Agent against Human Kidney Carcinoma Cells

Biological Evaluation of Oxindole Derivative as a Novel Anticancer Agent against Human Kidney Carcinoma Cells

Renal cell carcinoma has emerged as one of the leading causes of cancer-related deaths in the USA. Here, we examined the anticancer profile of oxindole derivatives (SH-859) in human renal cancer cells. Targeting 786-O cells by SH-859 inhibited cell growth and affected the protein kinase B/mechanisti...

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Bibliographic Details
Main Authors: Prasanta Dey, Amit Kundu, Sang Hoon Han, Kyeong-Seok Kim, Jae Hyeon Park, Sungpil Yoon, In Su Kim, Hyung Sik Kim
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomolecules
Subjects:
oxindole derivative
apoptosis
autophagy
glycolysis
tumor xenograft
Online Access:https://www.mdpi.com/2218-273X/10/9/1260

Internet

https://www.mdpi.com/2218-273X/10/9/1260

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