Deciphering the Rules Underlying Xenogeneic Silencing and Counter-Silencing of Lsr2-like Proteins Using CgpS of Corynebacterium glutamicum as a Model
In actinobacteria, Lsr2-like nucleoid-associated proteins function as xenogeneic silencers (XS) of horizontally acquired genomic regions, including viral elements, virulence gene clusters in Mycobacterium tuberculosis, and genes involved in cryptic specialized metabolism in Streptomyces species. Con...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2020-02-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.02273-19 |