Interaction between the triglyceride lipase ATGL and the Arf1 activator GBF1.

The Arf1 exchange factor GBF1 (Golgi Brefeldin A resistance factor 1) and its effector COPI are required for delivery of ATGL (adipose triglyceride lipase) to lipid droplets (LDs). Using yeast two hybrid, co-immunoprecipitation in mammalian cells and direct protein binding approaches, we report here...

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Bibliographic Details
Main Authors: Emy Njoh Ellong, Krishnakant G Soni, Quynh-Trang Bui, Rachid Sougrat, Marie-Pierre Golinelli-Cohen, Catherine L Jackson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3138737?pdf=render