Cryptococcus neoformans Chitin Synthase 3 Plays a Critical Role in Dampening Host Inflammatory Responses

Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or the inability of the host’s immune system to...

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Bibliographic Details
Main Authors: Camaron R. Hole, Woei C. Lam, Rajendra Upadhya, Jennifer K. Lodge
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.03373-19