Neuroprotective Effect of IRL-1620, an Endothelin B Receptor Agonist, on a Pediatric Rat Model of Middle Cerebral Artery Occlusion

Neuroprotective Effect of IRL-1620, an Endothelin B Receptor Agonist, on a Pediatric Rat Model of Middle Cerebral Artery Occlusion

Objective: The purpose of this study was to determine the potential neuroprotective effect of endothelin B (ETB) receptor agonist IRL-1620 treatment in a pediatric model of ischemic stroke.Design: A prospective, animal model study.Setting: An experimental laboratory.Subjects: Three-month-old male Wi...

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Bibliographic Details
Main Authors: Enrique G. Cifuentes, Mary G. Hornick, Suresh Havalad, Ramona L. Donovan, Anil Gulati
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pediatrics
Subjects:
stroke
cerebral blood flow
endothelin B receptor agonists
ischemic penumbra
cerebral infarction
reperfusion
Online Access:https://www.frontiersin.org/article/10.3389/fped.2018.00310/full

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https://www.frontiersin.org/article/10.3389/fped.2018.00310/full

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