Hormonal Responses to Cholinergic Input Are Different in Humans with and without Type 2 Diabetes Mellitus.

Hormonal Responses to Cholinergic Input Are Different in Humans with and without Type 2 Diabetes Mellitus.

Peripheral muscarinic acetylcholine receptors regulate insulin and glucagon release in rodents but their importance for similar roles in humans is unclear. Bethanechol, an acetylcholine analogue that does not cross the blood-brain barrier, was used to examine the role of peripheral muscarinic signal...

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Bibliographic Details
Main Authors: Sara Chowdhury, Songyan Wang, Judit Dunai, Rachel Kilpatrick, Lauren Z Oestricker, Michael J Wallendorf, Bruce W Patterson, Dominic N Reeds, Burton M Wice
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4909255?pdf=render

Internet

http://europepmc.org/articles/PMC4909255?pdf=render

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