Increased Cerebrospinal Fluid Levels of Ubiquitin Carboxyl-Terminal Hydrolase L1 in Patients with Alzheimer's Disease
Background: Dysfunctions of the ubiquitin proteasome system (UPS), including the highly abundant neuronal enzyme ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1), and autophagy-related changes (lysosomal degradation) are implicated in several neurodegenerative disorders including Alzheimer's d...
Main Authors: | Annika Öhrfelt, Per Johansson, Anders Wallin, Ulf Andreasson, Henrik Zetterberg, Kaj Blennow, Johan Svensson |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2016-07-01
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Series: | Dementia and Geriatric Cognitive Disorders Extra |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/447239 |
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