Dominant cross-reactive B cell response during secondary acute dengue virus infection in humans.

The four serotypes of dengue virus (DENV) cause dengue fever (DF) and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). Severe disease has been associated with heterotypic secondary DENV infection, mediated by cross-reactive antibodies (Abs) and/or cross-reactive T cells. The role of cross-r...

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Bibliographic Details
Main Authors: Simona Zompi, Magelda Montoya, Marie O Pohl, Angel Balmaseda, Eva Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3308930?pdf=render