Lipid-Iron Nanoparticle with a Cell Stress Release Mechanism Combined with a Local Alternating Magnetic Field Enables Site-Activated Drug Release

Lipid-Iron Nanoparticle with a Cell Stress Release Mechanism Combined with a Local Alternating Magnetic Field Enables Site-Activated Drug Release

Most available cancer chemotherapies are based on systemically administered small organic molecules, and only a tiny fraction of the drug reaches the disease site. The approach causes significant side effects and limits the outcome of the therapy. Targeted drug delivery provides an alternative to im...

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Bibliographic Details
Main Authors: Tuula Peñate Medina, Mirko Gerle, Jana Humbert, Hanwen Chu, Anna-Lena Köpnick, Reinhard Barkmann, Vasil M. Garamus, Beatriz Sanz, Nicolai Purcz, Olga Will, Lia Appold, Timo Damm, Juho Suojanen, Philipp Arnold, Ralph Lucius, Regina Willumeit-Römer, Yahya Açil, Joerg Wiltfang, Gerardo F. Goya, Claus C. Glüer, Oula Peñate Medina
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
theranostic
stimuli responsive release
liposome
acid sphingomyelinase (ASMase)
drug delivery
molecular imaging
Online Access:https://www.mdpi.com/2072-6694/12/12/3767

Internet

https://www.mdpi.com/2072-6694/12/12/3767

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