A systematic review and meta-analysis of the protective effects of metformin in experimental myocardial infarction.

Metformin improves cardiovascular prognosis in patients with diabetes mellitus, compared to alternative glucose-lowering drugs, despite similar glycemic control. Direct cardiovascular protective properties have therefore been proposed, and studied in preclinical models of myocardial infarction. We n...

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Bibliographic Details
Main Authors: Nienke A Hesen, Niels P Riksen, Bart Aalders, Michelle AE Brouwer, Merel Ritskes-Hoitinga, Saloua El Messaoudi, Kimberley E Wever
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5568412?pdf=render