Differential Efficacy of Novel Antiviral Substances in 3D and Monolayer Cell Culture

Repurposing of approved drugs that target host functions also important for virus replication promises to overcome the shortage of antiviral therapeutics. Mostly, virus biology including initial screening of antivirals is studied in conventional monolayer cells. The biology of these cells differs co...

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Bibliographic Details
Main Authors: Robert Koban, Markus Neumann, Philipp P. Nelson, Heinz Ellerbrok
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/11/1294