The Pro-Tumoral Activity of Heparan Sulfate 3-O-Sulfotransferase 3B (HS3ST3B) in Breast Cancer MDA-MB-231 Cells Is Dependent on the Expression of Neuropilin-1

The Pro-Tumoral Activity of Heparan Sulfate 3-O-Sulfotransferase 3B (HS3ST3B) in Breast Cancer MDA-MB-231 Cells Is Dependent on the Expression of Neuropilin-1

Heparan sulfate 3-O-sulfotransferases (HS3STs) catalyze the maturation step of heparan sulfate (HS) 3-O-sulfation. This modification is relatively rare. Moreover, only a few biological processes have been described to be influenced by 3-O-sulfated HS, and few ligands have been identified so far. Amo...

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Bibliographic Details
Main Authors: Charles Hellec, Mariama Diawara, Mathieu Carpentier, Agnès Denys, Fabrice Allain
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Molecules
Subjects:
heparan sulfate
sulfotransferase
neuropilin
cancer
Online Access:http://www.mdpi.com/1420-3049/23/10/2718

Internet

http://www.mdpi.com/1420-3049/23/10/2718

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